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RENAL FUNCTION IN CYSTIC FIBROSIS WITH SPECIAL REFERENCE TO THE RENAL SODIUM HANDLING
Author(s) -
BERG U.,
KUSOFFSKY E.,
STRANDVIK B.
Publication year - 1982
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1982.tb09528.x
Subject(s) - medicine , renal function , renal sodium reabsorption , sodium , reabsorption , cystic fibrosis , filtration fraction , endocrinology , renal physiology , kidney , urology , urinary system , renal blood flow , chemistry , organic chemistry
. Renal function was studied in 16 patients with cystic fibrosis, aged 5 to 19 years. The mean glomerular filtration rate and filtration fraction were increased compared to those in controls. Basal urinafy sodium excretion as well as renal responses to oral and intravenous sodium loads were low, indicating an increased renal sodium reabsorption. Diluting capacity, measured as free water clearance, was decreased because of a low distal sodium delivery which might indicate an increased proximal sodium reabsorption.