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SUPPRESSION OF AEROBIC AND ANAEROBIC FAECAL FLORA IN NEWBORNS RECEIVING PARENTERAL GENTAMICIN AND AMPICILLIN
Author(s) -
BENNET R.,
ERIKSSON M.,
NORD C. E.,
ZETTERSTRÖM R.
Publication year - 1982
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1982.tb09474.x
Subject(s) - gentamicin , anaerobic exercise , medicine , ampicillin , aerobic bacteria , anaerobic bacteria , antibiotics , klebsiella pneumoniae , parenteral nutrition , gestational age , microbiology and biotechnology , bacteria , physiology , pregnancy , escherichia coli , biology , biochemistry , genetics , gene
. The immediate effect of parenteral antibiotic treatment (gentamicin and ampicillin) on the aerobic and anaerobic faecal flora of 14 infants with suspected or proven neonatal septicaemia was studied. Eight infants of similar gestational and postnatal age were studied for comparison. All control infants showed an abundant growth of both aerobic and anaerobic bacteria as early as the first 2 weeks of life. The treated infants generally had lower counts of aerobic and especially of anaerobic bacteria; in 10 of 16 cultures no anaerobes were isolated. In relation to aerobic strains E. coli dominated in untreated infants and Klebsiella pneumoniae in treated ones.