Premium
NORMAL MICROBICIDAL FUNCTION OF MONOCYTES IN A GIRL WITH CHRONIC GRANULOMATOUS DISEASE
Author(s) -
WEEMAES C.,
LEIJH P.,
ALBLAS D. BLUSSÉ VAN OUD,
MEER J. VAN DER,
FURTH R. VAN
Publication year - 1981
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1981.tb16578.x
Subject(s) - medicine , chronic granulomatous disease , girl , monocyte , disease , immunology , granulomatous disease , function (biology) , pathology , genetics , biology
. Weemaes, C., (Department of Paediatrics, University Hospital, Nijmegen, The Netherlands), Leijh, P., Blusse van Oud Alblas, D., van der Meer, J. and van Furth, R. (Department of Infectious Diseases, University Hospital, Leiden, The Netherlands). Normal microbicidal function of monocytes in a girl with chronic granulomatous disease. Acta Paediatr Scand, 70:421, 1981.–The history of a 13‐year‐old girl with a syndrome resembling Chronic Granulomatous Disease (C.G.D.) is described. Metabolic studies in granulocytes and monocytes classified the patient as having C.G.D. The granulocytes failed to kill Staphylococcus aureus and Candida Albicans; however, the killing of these microorganisms by the patient's monocytes was nearly normal. Family studies revealed no abnormalities in the phagocytic cells of the parents and the siblings.