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BLOOD TRANSFUSION: A POSSIBLE RISK FACTOR IN RETROLENTAL FIBROPLASIA
Author(s) -
CLARK CHRISTINE,
GIBBS JUDITH A. H.,
MANIELLO ROBERT,
OUTERBRIDGE EUGENE W.,
ARANDA JACOB V.
Publication year - 1981
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1981.tb05736.x
Subject(s) - medicine , incidence (geometry) , retinopathy of prematurity , gestational age , pediatrics , birth weight , blood transfusion , exchange transfusion , risk factor , surgery , pregnancy , physics , biology , optics , genetics
. Clark, C, Gibbs, J. A. H., Maniello, R., Outerbridge, E. W., and Aranda, J. V. (Department of Newborn Medicine, McGill University, Montreal Children's Hospital Research Institute, Montreal, Quebec, Canada). Blood transfusion: A possible risk factor in retrolental Fibroplasia. Acta Paediatr Scand, 70:535,.–The effect of blood transfusion on the occurrence of RLF was evaluated in 58 infants who weighed less than 1 001 g at birth (Group I) and 70 oxygen treated infants of various birth weights (Group 11). Although there was no significant difference between Group 1 infants with or without exchange transfusion as to birth weight, gestational age, duration of oxygen therapy, peak Po 2 's, or multiple births, there was a significantly increased incidence of pre‐retrolental fibroplasia in transfused over non‐transfused Group II infants. When Group II infants were stratified for prematurity and oxygen duration, this difference persisted in those not already at risk for RLF. This increased incidence of retinopathy in transfused infants suggests that blood transfusion may be a risk factor in the pathogenesis of RLF.