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CONGENITAL NEPHROTIC SYNDROME DETECTED BY HYPOTHYROID SCREENING
Author(s) -
FINNEGAN J. T.,
SLOSBERG E. J.,
POSTELLON D. C.,
PRIMACK W. A.
Publication year - 1980
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1980.tb07350.x
Subject(s) - medicine , congenital hypothyroidism , nephrosis , nephrotic syndrome , pediatrics , congenital nephrotic syndrome , euthyroid , incidence (geometry) , newborn screening , thyroid , endocrinology , kidney , physics , proteinuria , optics
. Finnegan, J., Slosberg, E., Postellon, D. and Primack, W. (Borgess Medical Center, Kalamazoo, Michigan and Children's Hospital of Michigan, Wayne State University School of Medicine, Detroit, Michigan, USA). Congenital nephrotic syndrome detected by hypothyroid screening. Acta Pediatr Scand, 69: 705, 1980.—An infant was evaluated for a low thyroxine value, detected on routine neonatal screening for congenital hypothyroidism. She was found to have the congenital nephrotic syndrome, and to be euthyroid with low thyroid binding globulin. Congenital nephrosis can be detected by neonatal screening programs which use thyroxine as the primary screening test, but not by those which use TSH. This may be important in those countries in which the incidence of congenital nephrosis approaches that of congenital hypothyroidism.