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LDL RECEPTOR STUDIES IN TERM AND PRE‐TERM INFANTS: MEASUREMENT OF STEROL SYNTHESIS IN CORD BLOOD LYMPHOCYTES
Author(s) -
ANDERSEN GUNNAR E.,
JOHANSEN KRISTIAN B.
Publication year - 1980
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1980.tb07324.x
Subject(s) - medicine , cord blood , term (time) , familial hypercholesterolemia , ldl receptor , receptor , cholesterol , sterol , endocrinology , lipoprotein , physics , quantum mechanics
. Andersen, G. E. and Johansen, K. B. (The Neonatal Department, Rigshospitalet, University of Copenhagen, Denmark). LDL receptor studies in term and pre‐term infants: Measurement of sterol synthesis in cord blood lymphocytes. Acta Paediatr Scand, 69: 577, 1980.—Low density lipoprotein (LDL) receptor activity was measured in lymphocytes from pre‐term and term infants in order to elucidate if the hypercholesterolemia found in pre‐term infants might be secondary to a block in cholesterol transport across the cell membrane, analogous to that seen in familial hypercholesterolemia (FH). LDL receptor activity was found to be fully developed in pre‐term infants and no different from that of term infants and of a normal adult control.