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IRON DEFICIENCY IN SICKLE CELL DISEASE
Author(s) -
RAO J. NAGARAJ,
SUR A. M.
Publication year - 1980
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1980.tb07089.x
Subject(s) - medicine , transferrin saturation , iron deficiency , disease , pediatrics , serum iron , cell , transferrin , sickle cell anemia , anemia , biochemistry , chemistry
. Nagaraj Rao, J. and Sur, A. M. (Department of Paediatrics, Medical College and Hospital, Nagpur, India). Iron deficiency in sickle cell disease. Acta Paediatr Scand, 69:337, 1980.—Iron studies were performed on 25 children with homozygous sickle cell disease. The majority (80%) of patients had never been transfused. Surprisingly, the results showed that all had low serum iron and low transferrin saturation. Three children had no marrow iron stores while the rest had diminished amounts of iron. This may be an important finding in view of recent efforts at fortifying common salt with iron. The exact effects of iron deficiency on sickle cell disease are not known and a controlled trial is called for.