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SERUM PROLACTIN LEVELS IN RENAL INSUFFICIENCY IN CHILDREN
Author(s) -
IJAIYA KUNLE,
ROTH BERND,
SCHWENK ALFRED
Publication year - 1980
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1980.tb07082.x
Subject(s) - prolactin , medicine , endocrinology , basal (medicine) , hormone , kidney disease , creatinine , insulin
. Ijaiya, K., Roth, B. and Schwenk, A. (The University Children's Hospital, University of Cologne, Cologne, Federal Republic of Germany). Serum porlactin levels in renal insufficiency in children. Acta Paediatr Scand, 69: 299, 1980.—Basal prolactin concentrations in forty‐eight children with acute or chronic renal disease have been compared with those in thirty‐four healthy control subjects. Elevated basal prolactin levels and an abnormal prolactin response to intravenous thyrotropin‐releasing hormone were found in children with chronic renal failure on maintenance intermittent haemodialysis. No significant change in plasma prolactin concentrations and osmolality was observed before and after haemodialysis, despite a fall in plasma creatinine concentrations. The elevated prolactin levels fell to normal in three patients after successful renal transplantation. It is suggested that the kidney has an important role to play in prolactin metabolism.