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A PROSPECTIVE STUDY OF URINARY PROTEINS IN EARLY INFANCY
Author(s) -
KARLSSON F. ANDERS,
HARDELL LARSIVAR,
HELLSING KRISTOFFER
Publication year - 1979
Publication title -
acta paediatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1979.tb18435.x
Subject(s) - medicine , creatinine , beta 2 microglobulin , urinary system , albumin , prospective cohort study , renal function , serum albumin , kidney , pediatrics , endocrinology
. Karlsson, F. A., Hardell, L.‐I., and Hellsing, K. (Departments of Clinical Research, Internal Medicine, Paediatrics and Clinical Chemistry, University Hospital, Uppsala, Sweden). A prospective study of urinary proteins in early infancy. Acta Paediatr Scand, 68: 663, 1979.—Urinary concentrations of protein, albumin, β 2 ‐microglobulin, α‐amino nitrogen, and creatinine were determined in forty‐one full‐term infants on seven occasions up to six months of age. Except for β 2 ‐microglobulin the concentrations were highest on the first day, followed by a rapid decrease to a constant level within two weeks. Protein diminished approximately seven‐fold, albumin twenty‐fold, α‐amino nitrogen three‐fold and creatinine five‐fold. By contrast, β 2 ‐microglobulin, a low molecular weight protein, first increased three‐fold between day 1 and day 5, thereafter decreasing slowly 17‐fold during the first three months of age. The data indicate that different kidney functions mature asynchronously.