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EFFECT OF PREGNANCY ANAEMIA ON CELLULAR GROWTH IN THE HUMAN PLACENTA
Author(s) -
MARWAH PURNIMA,
SINOLA P. N.,
KRISHNA MEENAKSHI,
AGARWAL K. N.
Publication year - 1979
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1979.tb08230.x
Subject(s) - placenta , pregnancy , medicine , andrology , birth weight , cell , fetus , biology , biochemistry , genetics
. The effects of pregnancy anaemia on cell number and size in human placentae were investigated. Total organ weight, protein, RNA and DNA contents were determined in 54 fresh placentae from anaemic women (haemoglobin <110 g/l) and another 32 placentae from women without anaemia (haemoglobin 110 g/l). The placental weight was significantly reduced in pregnancy anaemia. The decrease in total placental DNA in anaemic women suggested that the reduced placental weight was due to a decrease in cell number. However, these placentae also showed evidence of compensatory cellular hypertrophy as indicated by increase in both weight per cell and protein per cell.