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MULTIPLE PITUITARY HORMONE DEFICIENCIES IN EIGHT SIBLINGS OF ONE JEWISH MOROCCAN FAMILY
Author(s) -
ADLERBIER M.,
PERTZELAN A.,
LARON Z.,
LIEBERMAN E.,
MOSES S.
Publication year - 1979
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1979.tb05027.x
Subject(s) - medicine , etiology , sibling , endocrinology , judaism , hormone , pituitary gland , pituitary hormones , physiology , pediatrics , developmental psychology , psychology , archaeology , history
. In a Jewish Moroccan inbred family, 8 of 12 siblings were found to have multiple deficiencies of pituitary hormones, including GH, TSH and gonadotrophins. The parents showed no deficiency and are in good health, as are the other 4 siblings. The investigations carried out indicate that in this family the etiology is hereditary in nature, probably being autosomal recessive, with the defect located in the pituitary gland.