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RENAL FUNCTION IN INFANTS WITH HYPERBILIRUBINEMIA
Author(s) -
BROBERGER U.,
APERIA A.
Publication year - 1979
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1979.tb04433.x
Subject(s) - medicine , bilirubin , renal function , gestational age , unconjugated hyperbilirubinemia , pediatrics , urinary system , renal physiology , sodium , serum bilirubin , excretion , gastroenterology , physiology , endocrinology , pregnancy , chemistry , genetics , organic chemistry , biology
. Broberger, U. & Aperia, A. (Departments of Paediatrics at Karolinska Sjukhuset and St. Göran's Children's Hospital, Stockholm, Sweden). Renal function in infants with hyperbilirubinemia. Acta Paediatr Scand, 68, 1979.—A total of 45 infants were studied on the fourth or fifth day of life: 13 term and 10 pre‐term infants with serum bilirubin levels ranging between 257 and 390 µmol/l were compared with 12 term and 10 pre‐term infants with serum bilirubin levels below 195 µmol/l. The groups did not differ with regard to mean gestational age or mean post‐natal age. GFR and C PAH were determined with the single injection clearance method and ability to excrete Na + was determined following an oral loading of sodium chloride. GFR was lower in infants with hyperbilirubinemia and correlated negatively to the highest recorded serum bilirubin value. C PAH was similar in hyperbilirubinemic infants and controls. The urinary sodium excretion was significantly higher in infants with hyperbilirubinemia.