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RENAL FUNCTION IN IDIOPATHIC RESPIRATORY DISTRESS SYNDROME
Author(s) -
BROBERGER U.,
APERIA A.
Publication year - 1978
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1978.tb16327.x
Subject(s) - medicine , respiratory distress , excretion , gestational age , urinary system , endocrinology , renal function , pediatrics , gastroenterology , physiology , anesthesia , pregnancy , biology , genetics
. Renal function was studied in 11 pre‐term infants with idiopathic respiratory distress syndrome (IRDS) grade 1 according to Prod'hom's criteria. As a reference 16 healthy pre‐term infants were studied. The groups did not differ with regard to mean gestational age (GA) and mean postnatal age (PNA). The studies were preformed twice, first at a PNA of 33–37 hours and then at 132–148 hours. GFR and C PAH were determined with the single injection technique and the ability to excrete Na was determined following an oral Na + load. GFR was higher in IRDS infants at the first investigation and slightly lower in IRDS infants at the second investigation. The GFR correlated to the lowest recorded P ao2 r=0.45) in IRDS infants. C PAH was similar in IRDS and controls at the first, and lower in IRDS infants at the second investigation. The urinary Na + excretion was significantly higher in IRDS infants. Treatment with digitalis was in part responsible for the high urinary Na + excretion. The IRDS infants had a higher Na + and glucose intake than the control infants. It is suggested that this higher intake is in part responsible for the relatively high GFR and urinary Na + excretion in the IRDS infants.