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IMMUNOSUPPRESSIVE MEASLES ENCEPHALOPATHY
Author(s) -
PEDERSEN F. KARUP,
SCHIØTZ P. O.,
VALERIUS N. H.,
HERTZ H.
Publication year - 1978
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1978.tb16286.x
Subject(s) - medicine , encephalopathy , measles , virology , pediatrics , vaccination
. A Case of measles infection without a rash, which was followed by a severe encephalopathy after two months, is described in a 2½ year old boy. At the age of 8 months he had been irradiated for an inoperable intrathoracic neuroblastoma, and at the time of exposure to measles he was being treated with cyclophosphamide and vincristine. This case closely resembles other cases recently described and termed immunosuppressive measles encephalopathy. The syndrome is believed to represent the effect of measles virus in patients with deficient cellular immunity induced by antineoplastic treatment. The importance of protecting children on immunosuppressive treatment from contracting measles is stressed.