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ATOPIC DISEASE IN SEVEN‐YEAR‐OLD CHILDREN Incidence in Relation to Family History
Author(s) -
KJELLMAN N.I. MAX
Publication year - 1977
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1977.tb07928.x
Subject(s) - medicine , incidence (geometry) , asthma , family history , disease , pediatrics , respiratory disease , atopy , allergy , immunology , lung , physics , optics
. The incidence of atopic disease and its relation to the family history was studied by questionnaire in 1325 children, 7 years of age. A higher incidence of bronchial asthma (2.7%) was found than in a previous Swedish study. The total incidence of atopic disease in the children was 15.1% with a higher level when there was a double parental history of such disease (42.9%) as compared with a single such history (19.8%). When both parents had an identical type of atopic disease, i.e. respiratory or skin, the incidence of atopic disease was higher (72.2%) than when non‐identical types occurred in the parents (20.8%). The findings support theories of a polygenic transmission of atopic disease as well as a genetic influence on symptom specificity in such disease and may be of value in genetic counselling.