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INSULIN AND GROWTH HORMONE SECRETION IN A LEUKAEMIC GIRL WITH HYPOTHALAMIC SYNDROME
Author(s) -
SCHILIRÒ G.,
RUSSO A.,
SCIOTTO A.,
VIGO R.
Publication year - 1977
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1977.tb07846.x
Subject(s) - medicine , insulin , endocrinology , girl , hormone , growth hormone , secretion , biology , genetics
Schilirò, G., Russo, A., Sciotto, A. and Vigo, R. (Paediatric Clinics I and II, University of Catania, Catania, Italy). Insulin and growth hormone secretion in a leukaemic girl with hypothalamic syndrome. Acta Paediatr Scand, 66:261, 1977.—The authors report a girl with acute lymphoblastic leukaemia presenting hypothalamic syndrome characterized by meningeal leukaemia, hyperphagia and obesity. Insulin and growth hormone secretion, studied with arginine and insulin stimulation tests, showed a high peak of serum insulin and no response of growth hormone. Insulin and growth hormone responses to these tests reverted to normal after intrathecal methotrexate.