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CHANGES IN ERYTHROCYTE LIPID STROMA IN THE PREMATURE INFANT ACCORDING TO DIETARY FAT COMPOSITION
Author(s) -
BALLABRIGA A.,
MARTINEZ M.
Publication year - 1976
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1976.tb04958.x
Subject(s) - calorie , linoleic acid , medicine , oleic acid , composition (language) , food science , fatty acid , zoology , biochemistry , biology , linguistics , philosophy
. Eighteen premature infants of similar gestational age, divided into three groups, were fed 3 milk formulas containing different amounts of linoleic acid. All the cases received 120 calories per kg of weight and day, of which formula A supplied 6.1% of the dietary total calories as linoleic acid, formula B 15.9% and formula C only 0.6%. The fatty acids of red cell ethanolamine and choline phosphoglycerides were studied in a first sample obtained during the first hours of life before the infants had received any food, and in a second sample taken at the age of three weeks. In the group fed formula C (0.6% of the total calories) changes similar to those described in EFA‐deficient rats were found, namely, a decrease of linoleic acid, and an increase of oleic acid and of 20: 3 ( n ‐9), with a consequent rise of the triene to tetraene ratio. When the supply of linoleate was highest (15.9% of the total caloric intake) linoleic acid increased, oleic acid decreased and the 20: 3 ( n ‐9) practically disappeared. None of the three groups showed any clinical symptoms.