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CLINICAL AND CYTOGENETIC STUDIES IN UNDESCENDED TESTES
Author(s) -
WAALER P. E.
Publication year - 1976
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1976.tb04931.x
Subject(s) - medicine , muscle hypertrophy , inguinal hernia , epididymis , testicular volume , klinefelter syndrome , hernia , urology , surgery , andrology , hormone , sperm , secondary sex characteristic
. 168 boys aged 2.5–16.8 years with unilateral or bilateral undescended testes or anorchia were studied. Retention was severe (canalicular or intraabdominal) in 1/4 and moderate in 3/4 of the cases. In unilateral retention, the volume of the scrotal testis was usually normal throughout childhood whereas pubertal testicular growth was delayed. In unilateral anorchia, the scrotal testis showed compensatory hypertrophy. In all age groups examined, the mean volume of the undescended testes was abnormally small. Undescended testes were accompanied by abnormalities of the epididymis in 3.6% of cases, of the ductus deferens in 7.8% and of the spermatic vessels in 8.3%. In anorchia such abnormalities were found regularly. Inguinal hernia accompanied 62.8% of the undescended testes and was most frequent in severe cases. Patients aged 8.0–9.9 years with unilateral undescended testis had advanced bone age. Cytogenetic investigations of 167 patients revealed one case of Klinefelter's syndrome (47, XXY). Gonadotrophin treatment was tried in 50 patients and was successful in 12. Surgical results were satisfactory in 86.1% of the operated testes.