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SERUM LYSOZYME ACTIVITY IN CHILDREN WITH HEMATOLOGICAL AND MALIGNANT DISORDERS
Author(s) -
MOE PETER JOHAN,
HANEBERG BJøRN,
FINNE PER H.
Publication year - 1975
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1975.tb03932.x
Subject(s) - medicine , lysozyme , leukemia , acute lymphocytic leukemia , acute leukemia , complete remission , pediatrics , gastroenterology , lymphoblastic leukemia , immunology , chemotherapy , genetics , biology
Moe, P. J., Haneberg, B. and Finne, P. H. (Department of Paediatrics, University of Tromsø, Tromsø and Department of Paediatrics, University of Bergen, Bergen, Norway). Serum lysozyme activity in children with hematological and malignant disorders. Acta Paediatr Scand, 64: 830, 1975.–Pretreatment serum lysozyme activity was high in 2 children with myelomonocytic leukemia, 800 and 1000′/ig/ml, normal in all 10 cases of acute myelocytic leukemia and subnormal in 21 of 34 cases of acute lymphocytic leukemia. Normal values were found in all but one case of acute lymphocytic leukemia during complete remission including 8 cases after all therapy had been discontinued. All 8 are still in complete remission. Low serum lysozyme activity was found in 5 patients with acute lymphocytic leukemia in complete relapse, this could possibly be helpful in the diagnosis of early relapse. Activity was subnormal in 5 of 17 children with malignant tumours, and in 3 of 65 cases of various benign hematological disorders.