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FANCONI'S ANEMIA II.
Author(s) -
STUBBE P.,
PRINDULL G.
Publication year - 1975
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1975.tb03925.x
Subject(s) - medicine , fanconi anemia , endocrine system , anemia , testosterone (patch) , pediatrics , disease , hormone , endocrinology , genetics , gene , dna repair , biology
Stubbe, P. and Prindull, G. (Department of Paediatrics, University of Goet‐tingen, D 34 Gottingen, Kinderklinik, BRD): Fanconi's anemia. II. Are multiple endocrine insufficiencies a substantial part of the disease? Acta Paediatr Scand, 64: 790, 1975. –Three children with Fanconi's anemia belonging to a family where 6 children had the disease were investigated. One child had growth hormone deficiency, a second child showed subnormal response of testosterone to gonadotropin stimulation and the third child had a missing insulin release following arginine. This report shows that growth hormone deficiency is not necessarily linked with Fanconi's anemia when it occurs in a family. Multiple endocrine insufficiencies do not appear to be part of the disease.