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PLASMA ADRENALIN IN A CHILD WITH KETOTIC HYPOGLYCEMIA AND CALCIFICATIONS OF THE SUPRARENAL GLANDS
Author(s) -
JACOBSEN B. BROCK,
KASTRUP K. W.,
CHRISTENSEN N. JUEL
Publication year - 1975
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1975.tb03881.x
Subject(s) - hypoglycemia , medicine , endocrinology , epinephrine , urinary system , plasma glucose , pediatrics , insulin
Jacobsen, B. B., Kastrup, K. W. and Christensen, N. J. (Childrens Hospital Fuglebakken, Copenhagen, and 2nd Clinic of Internal Medicine, Kommunehospitalet, Aarhus, Denmark). Plasma adrenalin in a child with ketotic hypoglycemia and calcifications of the suprarenal glands. Acta Paediatr Scand, 64:559, 1975.–Urinary excretion of adrenalin has been reported to be reduced during insulin‐induced hypoglycemia in a significant proportion of children having ketotic hypoglycemia. By employing a sensitive double‐isotope derivative technique, plasma adrenalin and plasma noradrenalin were determined in a boy 6 years 9 months old who had had ketotic hypoglycemia with intermittent hypoglycemic symptoms from the age of 10 months. Bilateral calcifications of the suprarenal glands were present. The adrenocortical function was normal. The plasma adrenalin response to hypoglycemia were practically absent, being only 4 % of the value obtained in healthy children. The results were related to previous findings of a low plasma adrenalin response in patients with ketotic hypoglycemia without adrenal calcifications and support the assumption that ketotic hypoglycemia is associated with hypoadrenalinemia.