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COMPLEMENT FIXING AND LYMPHOCYTOTOXIC ANTIBODIES IN SERUM OF PREGNANT WOMEN AT DELIVERY
Author(s) -
GUNNARNYMANDM
Publication year - 1975
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1975.tb03875.x
Subject(s) - medicine , antibody , immunology , cord blood , pregnancy , wiskott–aldrich syndrome , obstetrics , genetics , biology , biochemistry , chemistry , gene
Nymand, G. (Regional Blood Transfusion Center, Aalborg, Denmark). Complement fixing and lymphocytotoxic antibodies in serum of pregnant women at delivery, HI. Acta Paediatr Scand 64:531, 1975.–The investigation comprised 2008 pregnancies. Sera from all the pregnant women were examined for complement fixing platelet antibodies (CFPAb) and lymphocytotoxic antibodies (LCTAb). 14 women had only CFPAb, 44 had CFPAb and LCTAb, 224 had only LCTAb. In 3 of 481 cord blood serum samples LCTAb were demonstrated. No cases of neutropenia or thrombocytopenia were observed. No association was found between CFPAb or LCTAb and stillbirth, birth defects, degree of bilirubinaemia, diseases of the newborn, or placental weight. It was suggested that the applied lymphocytotoxicity test detects both in vivo cytolytic antibodies and enhancing antibodies, which may explain the results.