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LACK OF RELATIONSHIP OF RED CELL ENZYME ACTIVITY TO BILIRUBIN AND CARBOXYHEMOGLOBIN LEVELS IN HEALTHY TERM INFANTS
Author(s) -
KOMAZAWA MASARU,
LANDAW STEPHEN A.,
OSKI FRANK A.
Publication year - 1975
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1975.tb03867.x
Subject(s) - bilirubin , carboxyhemoglobin , medicine , hemolysis , red cell , enzyme , hemoglobin , glucose 6 phosphate dehydrogenase , endocrinology , biochemistry , dehydrogenase , biology , catalysis , carbon monoxide
Komazawa, M., Landaw, S. A. and Oski, F. A. (Departments of Pediatrics and Medicine, State University of New York, Upstate Medical Center, Syracuse, New York, USA). Lack of relationship of red cell enzyme activity to bilirubin and carboxyhemoglobin levels in health term infants. Acta Paediatr Scand 64:473, 1975.–A total of 32 term infants were studied in an attempt to confirm and extend the recent observation of Petrich & associates (14) that minor degrees of transient deficiencies of the red cell enzymes glucose phosphate isomerase and glyceraldehyde‐3‐phosphate dehydrogenase were related to hyperbilirubinemia in otherwise healthy term infants. No relationships could be observed between the activity of these enzymes and the bilirubin level on day three. In addition, no correlation was present between bilirubin values and carboxyhemoglobin levels on day three, suggesting that in the healthy term infant excessive hemolysis is not usually responsible for the variations observed in bilirubin levels.