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COAGULATION CHANGES ASSOCIATED WITH A HIGH HAEMATOCRIT IN THE NEWBORN INFANT
Author(s) -
RIVERS R. P. A.
Publication year - 1975
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1975.tb03864.x
Subject(s) - medicine , coagulation , disseminated intravascular coagulation , coagulation testing , exchange transfusion , hematology , hematocrit , fibrin , pediatrics , fibrinogen , intensive care medicine , immunology
Rivers, R. P. A. (Departments of Paediatrics and Clinical Haematology, University College Hospital Medical School, London W.C.I, England). Coagulation Changes Associated with a High Haematocrit in the Newborn Infant. Acta Paediatr Scand, 64:449, 1975.–Sequential blood coagulation studies were performed on samples from three newborn infants with venous haematocrit values of over 65%. Combinations of thrombocytopaenia, circulating fibrin monomer and evidence of intravascular thromboplastic activity were found. Reduction of the haematocrit value by partial exchange transfusion in each infant was followed by improvement of the abnormal coagulation findings. Some possible mechanisms for the origin of the coagulation abnormalities are considered.