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POSTIRRADIATION SYNDROME AND EEG FINDINGS IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKAEMIA
Author(s) -
GARWICZ S.,
ARONSON A. S.,
ELMQVIST D.,
LANDBERG T.
Publication year - 1975
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1975.tb03854.x
Subject(s) - medicine , electroencephalography , pediatrics , clinical neurophysiology , radiation therapy , psychiatry
Garwicz, S., Aronson, A. S., Elmqvist, D. and Landberg, T. (Departments of Paediatrics, Clinical Neurophysiology, Radiotherapy, University Hospital, Lund, Sweden). Postirradiation syndrome and EEG findings in children with acute lymphoblastic leukaemia. Acta Paediatr Scand, 64:399, 1975.–Out of 12 children with acute lymphoblastic leukaemia treated with craniospinal irradiation during primary haematologic remission, 8 developed a postirradiation syndrome characterized by fever and tiredness. The symptoms lasted 1–2 weeks and subsided spontaneously. Longitudinal EEG studies revealed no acute disturbances during the irradiation therapy but in all cases studied, moderate to severe diffuse general slowing developed during the postirradiation syndrome. Complete normalization of the EEG occurred in all children at follow‐up. It is concluded that the described EEG abnormalities constitute an integral part of the postirradiation syndrome.