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UTILIZATION OF FAT EMULSION DURING TOTAL PARENTERAL NUTRITION IN CHILDREN
Author(s) -
FORGET P. P.,
FERNANDES J.,
BEGEMANN P. HAVERKAMP
Publication year - 1975
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1975.tb03851.x
Subject(s) - medicine , fat emulsion , parenteral nutrition , discontinuation , lipoprotein lipase , endocrinology , zoology , adipose tissue , biology
Forget, P., Fernandes, J. and Haverkamp Begemann, P. (Department of Paediatrics, Sophia Children's Hospital and Neonatal Unit, Erasmus University, Rotterdam, the Netherlands). Utilization of fat emulsion during total parenteral nutrition in children. Acta Paediatr Scand, 64: 377, 1975.–Tolerance for Intralipid fat emulsion during total parenteral nutrition (PN) was studied in 6 children. The Intralipid dose was monitored by the daily determination of plasma Intralipid levels. Fat removal was investigated at the start of and during the PN period by the intravenous fat tolerance test (IVFTT) and by determining the plasma postheparin lipoprotein lipase (LPL) activity. When the plasma Intralipid levels exceeded a value of 100 mg/100 ml, hyper pre‐βT lipoproteinaemia, hypertriglyceridaemia, hypercholesterolemia and hyperphospholipidaemia appeared. During PN most patients showed marked increases of postheparin LPL. Return to normal values occurred after discontinuation of PN. Maximal LPL activities were found to correlate significantly with total daily caloric intake ( r =0·95, 0.05

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