Premium
USE OF THE NITROBLUE TETRAZOLIUM (NBT) TEST IN THE DIFFERENTIATION BETWEEN PYELONEPHRITIS AND CYSTITIS
Author(s) -
BJÖRKSTÉN B.,
CHATEAU P.
Publication year - 1975
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1975.tb03819.x
Subject(s) - medicine , asymptomatic bacteriuria , asymptomatic , urinary system , urine , bacteriuria , acute cystitis , titer , gastroenterology , nitroblue tetrazolium , immunology , antibody
Björkstén, B. and de Chateau, P. (Department of Paediatrics, Umeå University, Umeå, Sweden.) Use of the Nitroblue Tetrazolium (NBT) Test in the differentiation between pyelonephritis and cystitis. Acta Paediatr Scand 64:182, 1975.– NBT tests were performed on blood from 37 patients with urinary tract infections caused by conform bacteria. The level of infections was evaluated by the clinical signs, ESR, renal concentrating capacity and titre of antibodies against the strains of E. coli isolated in their urine. Elevated proportions of NBT‐positive neutrophils were found in 11 of 14 patients with pyelonephritis and in 3 of 23 patients with cystitis or asymptomatic bacteriuria (ABU). The total number of NBT‐positive neutrophils was 1000 or more per mm 3 blood in 11 of 13 patients considered to have pyelonephritis, while it was 800 or less in all the patients investigated, evaluated as having cystitis or asymptomatic bacteriuria. The NBT test is recommended as an adjunct in the level diagnosis or urinary tract infections in children. The utility of the test in smouldering pyelonephritis is presently being investigated.