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A FOLLOW‐UP STUDY OF HYPERBILIRUBINAEMIA IN HEALTHY, FULL‐TERM INFANTS WITHOUT ISO‐IMMUNIZATION
Author(s) -
BENGTSSON B.,
VERNEHOLT J.
Publication year - 1974
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1974.tb04351.x
Subject(s) - medicine , exchange transfusion , jaundice , pediatrics , immunization , full term , serum bilirubin , bilirubin , surgery , pregnancy , immunology , antibody , biology , genetics
Summary With the aim of shedding light on the indications for exchange transfusion in healthy, full term infants without iso‐immunization, a detailed follow‐up investigation was made of 226 children, of whom 111 had had neonatal hyperbilirubinaemia with maxima) bilirubin values of 20–51 mg/100 ml and the other 115 (controls) had had no visible jaundice neonatally. The children underwent physical and neurological examinations as well as audiometric and psychological tests. Among the 111 children with neonatal hyperbilirubinaemia 2 had coordination disturbances of the athetotic type and 4 had sensorineural hearing impairment, while none of the 115 control children had such disorders. The differences in the frequencies of the e conditions were not statistically significant, however. Neither did the frequencies of subnormal intelligence and psychological disturbances in the two groups differ significantly. Exchange transfusion is recommended in healthy, full‐term infants without iso‐immunization as'a measure to prevent the serum bilirubin level from exceeding 25 mg 100 ml.