Premium
QTU‐ABNORMALITIES, SINUS BRADYCARDIA AND ADAMS‐STOKES ATTACKS DUE TO VENTRICULAR TACHYARRHYTHMIA
Author(s) -
BERNUTH GÖTZ VON,
BELZ GUSTAV G.,
EVERTZ WALTRAUD,
STAUCH MARTIN
Publication year - 1973
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1973.tb17086.x
Subject(s) - medicine , cardiology , sinus bradycardia , qt interval , bradycardia , repolarization , t wave , heart rate , proband , atropine , electrocardiography , anesthesia , electrophysiology , blood pressure , chemistry , biochemistry , mutation , gene
SUMMARY Tachyarrhythmic Adams‐Stokes attacks, provoked by physical and emotional stress, are reported in a 10‐year‐old girl with sinus brady‐cardia at rest, prominent U waves, a normal resting QT‐interval but QT‐prolongation on exercise. Two brothers, the father and the paternal grandmother have a slight QT‐prolongation but no attacks. In the proband, physical exercise and small doses of a beta‐adrenergic stimulator reliably cause ventricular bigemini and/or runs of multifocal ventricular extra‐systoles while increase in heart rate by Atropine and atrial pacing does not. The ventricular arrhythmia is improved by beta‐receptor blocking agents. It is proposed that in this and other patients with abnormal repolarization the ventricular myocardium is unduely sensitive to sympathetic stimuli, resulting in ventricular tachyarrhythmia.