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HUMAN GROWTH HORMONE THERAPY IN HYPOPITUITARISM DUE TO TUBERCULOUS MENINGITIS
Author(s) -
BARTSOCAS CHRISTOS S.,
PANTELAKIS STEFANOS N.
Publication year - 1973
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1973.tb08107.x
Subject(s) - medicine , hypopituitarism , tuberculous meningitis , meningitis , growth hormone deficiency , endocrine system , growth hormone , endocrinology , human growth hormone , pediatrics , hormone
Summary Lesions due to tuberculous meningitis resulting in endocrine dysfunction are not rare. They usually cause inappropriate ADH secretion, but occasionally other endocrinopathies related to the affected hypothalamic or pituitary regions are seen. Two female patients, 13 1 / 2 and 16 1 / 2 years old, treated in early childhood for tuberculous meningitis are presented. Both were very short and had intracranial calcifications; however, the hypothalamic area was involved in only one of the patients. Both had GH and ADH deficiency, while one of them had gonado‐tropin deficiency as well. Administration of HGH resulted in an adequate growth response.