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VIRUS SEROLOGY AND SERUM IgE LEVELS IN CHILDREN WITH ASTHMATOID BRONCHITIS
Author(s) -
FOUCARD T.,
BERG T.,
JOHANSSON S. G. O.,
WAHREN B.
Publication year - 1971
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1971.tb07001.x
Subject(s) - serology , medicine , immunology , immunoglobulin e , seroconversion , virus , bronchitis , asthma , eosinophilia , titer , antibody , virology
Summary Seventy‐two children with wheezing related to respiratory tract infections have been investigated regarding virus serology and serum IgE levels. Positive virus serology with the CF technique was achieved in 18 % to RS virus in spite of absence of epidemics. Seroconversion to ECHO‐viruses types 3, 6, 7, 9 and 11 was seen in altogether 18%. Antibody titers indicating infections with parainfluenzavirus, adenovirus or influenza A‐2 virus were found less frequently. Twenty‐one of the infants had high IgE levels and these infants had allergic heredity, recidivating symptoms, former atopic manifestations and eosinophilia in blood and secretions more often than the infants with normal IgE. Positive virus serology was found as often in the infants with high IgE as in those with normal IgE. Determinations of the serum IgE levels seem to be of value in assessing the possible atopic component in children with asthmatoid bronchitis.