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COMPARISON OF GLOMERULAR FILTRATION RATE AND EFFECTIVE RENAL PLASMA FLOW DETERMINATIONS OBTAINED BY A SINGLE INJECTION TECHNIQUE AND BY MEANS OF A STANDARD CLEARANCE TECHNIQUE IN CHILDREN
Author(s) -
VÖGELI B.,
RIEDWYL H.,
DONATH A.,
OETLIKER O.
Publication year - 1971
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1971.tb06985.x
Subject(s) - medicine , renal function , urology , effective renal plasma flow , inulin , renal blood flow , pah clearance , urinary system , urinary flow , clearance , chemistry , prostate , biochemistry , cancer
Summary In children 28 values for glomerular filtration rate and 25 values for effective renal plasma flow were simultaneously obtained by means of the inulin‐ and PAH‐clearance and by means of a single injection method with 51 Cr‐EDTA and 123 I‐OIH. These were compared in an appropriate statistical model. The results show good agreement of the two methods. The single injection method can therefore be of value in childhood when only values for GFR and effective renal plasma flow are asked or especially if inappropriate urinary collection is expected or bladder catheterisation is contraindicated. It has no place in studies concerned with renal physiology or pathophysiology.