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PURPURA AND ACETYLSALICYLIC ACID THERAPY
Author(s) -
DAELE MARIA CASTEELSVAN,
GAETANO G. DE
Publication year - 1971
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1971.tb06643.x
Subject(s) - medicine , purpura (gastropod) , platelet , thrombocytopenic purpura , thrombotic thrombocytopenic purpura , platelet aggregation , differential diagnosis , aspirin , gastroenterology , pathology , ecology , biology
Summary Three cases are reported of children presenting purpura while taking a normal dose of ace‐tylsalicylic acid since a few days. Studies of the platelet function showed an impaired platelet aggregation by an inhibition of ADP release. It is concluded that this mechanism is responsible for the clinical findings, and that an acetylsalicylic acid therapy should always be considered in the differential diagnosis of a non‐thrombocytopenic purpura.