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THE BEHAVIOUR OF SOME INDICES OF CALCIUM‐PHOSPHATE METABOLISM IN TURNER'S SYNDROME
Author(s) -
SZCZEPSKI O.,
WALCZAK M.,
MACIEJEWSKI J.,
BITTNER K.,
CZEKALSKI S.,
WALIGORA A.
Publication year - 1971
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1971.tb06620.x
Subject(s) - calcium , endocrinology , medicine , osteoporosis , turner syndrome , kidney , excretion , phosphate , turner's syndrome , metabolism , physiology , biology , biochemistry
Summary The results of calcium and parathormone loading tests in 6 individuals with Turner's syndrome indicate a certain degree of insensitive‐ness of the tissues, especially of the kidney, when compared with healthy individuals. A similar insensitiveness expressing itself by a decrease in hydrogen ion excretion was found after ammonium chloride loading. An analysis of the results suggest the existence in this syndrome of insensitiveness of renal tubules to regulatory factors. Osteoporosis and stunting of growth may be connected partly with intestinal calcium loss occurring at puberty, and partly with this insensitiveness to regulatory factors.