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REVERSIBLE ADRENAL UNRESPONSIVENESS IN A PATIENT WITH CONGENITAL ADRENAL HYPERPLASIA
Author(s) -
Kulin Howard E.,
Wilson Hildegard W.
Publication year - 1968
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1968.tb04671.x
Subject(s) - medicine , congenital adrenal hyperplasia , hyperplasia , endocrinology , adrenocortical hyperfunction , hydrocortisone
Summary A 7 1/2‐year‐old boy in whom the diagnosis of congenital adrenal hyperplasia was made at age 5 weeks is presented. Treatment with exogenous corticoids was started immediately, but between ages 1 to 4 an Addisonian state intervened. Classical congenital adrenal hyperplasia then reappeared after age 6, following a reduction in corticoid replacement. Suppression of ACTH by exogenous glucucorticoid is suggested as a possible cause of this reversible adrenal failure.