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Familial Leukaemia — Three Cases of Acute Leukaemia in Four Siblings
Author(s) -
LUNDMARK K. M.,
THILÉN ASTRID,
VAHLQUIST B.
Publication year - 1967
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1967.tb15297.x
Subject(s) - medicine , childhood leukaemia , etiology , pediatrics , myeloid leukaemia , immunology , pathology
Summary An instance of familial leukaemia is described where 3 children out of 4 died of acute lymphocytic leukaemia at the ages of 2–4 years. Two of the siblings were twins, probably binovular. Genetic mechanisms in the aetiology of acute leukaemia are discussed and the pertinent literature is briefly reviewed.