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QUANTITATIVE STUDIES OF THE HUMAN NEONATAL CIRCULATION
Author(s) -
WALLGREN GöRAN,
LIND JOHN
Publication year - 1967
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1967.tb05273.x
Subject(s) - medicine , hypovolemia , hematocrit , blood volume , blood pressure , systemic circulation , blood flow , vasomotor , perfusion , vascular resistance , hemodynamics , peripheral , hypervolemia , anesthesia , cardiology
Summary Twelve newborn infants, 1 1/2 to 58 hours old have been investigated with respect to the consequences of graded hemorrhage on peripheral circulation and plasma volume. It has been demonstrated that the newborn infant responds to a hypovolemia corresponding to 15 per cent of predicted total blood volume with a twofold increase of resistance to blood flow in the calf. Peripheral vasomotor tone is adequately controlling the systemic blood pressure by decreasing perfusion of the vascular compartments in the calf muscle, whereas no indications of a change in the cutaneous blood flow occurred. A rapid decrease of the arterial hematocrit reflects efforts to restore the plasma volume.