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Erythrocyte Cholinesterase Activity in Hemolytic Anemias
Author(s) -
CHOREMIS C.,
NICOLOPOULOS D.,
METAXOTOU K.,
MOSCHOS AL.,
AL C. CHOBEMIS ET
Publication year - 1965
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1965.tb06365.x
Subject(s) - medicine , hemolytic anemia , autoimmune hemolytic anemia , hemosiderosis , hereditary spherocytosis , anemia , aplastic anemia , cholinesterase , immunology , population , sickle cell anemia , disease , bone marrow , environmental health
Summary The erythrocyte cholinesterase activity was studied in 41 thalassemic children, 15 cases of microdrepanocytosis (sickle cellthalassemia disease), 13 cases with favism, children with autoimmune hemolytic anemia, 2 cases of congenital spherocytosis, 2 children with aplastic anemia and 4 with iron deficiency anemia, as well as in children with pulmonary hemosiderosis. The mean activity of the red cell acetylcholinesterase in thalassemics was lower than normal, although a considerable overlapping of the values existpd in 25 % the population of the anemic and control groups. The enzyme activity was found to be consistently low in the three cases of autoimmune hemolytic anemia studied, while there were no significant changes in the other hemolytic anemias.