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“Bacterial Allergy” in Childhood Asthma and the Effect of Vaccine Treatment
Author(s) -
AAS KJELL,
BERDAL PETER,
HENRIKSEN SVERRE DICK,
GARDBORG ODD
Publication year - 1963
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1963.tb03789.x
Subject(s) - medicine , allergy , placebo , asthma , immunology , pediatrics , pathology , alternative medicine
SUMMARY Asthmatic children with presumptive isolated bacterial allergy were selected for a placebo controlled study of the effect of treatment with bacterial vaccines. Of more than 400 children studied only 25 satisfying the criteria for the diagnosis “isolated bacterial allergy” were found. During the investigation period of 12–24 months repeated testings were performed and specific allergies were demonstrated in an additional 10 children out of the 25. At the start of the period active infectious rhinosinusitis was found in 16 of the 25 patients. Elimination of the infections resulted in marked improvement of the allergic symptoms in all but two children. There was no significant difference between the results in the vaccine and placebo groups. The side effects were also equally distributed between the two groups.