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Susceptibility to Infectious Disease, the Response to Active Immunization and the Antibody Titres in Diabetic Schoolchildren
Author(s) -
STERKY GÖRAN
Publication year - 1963
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1963.tb03778.x
Subject(s) - medicine , immunization , antibody response , immunology , antibody , disease , infectious disease (medical specialty) , virology
SUMMARY In a group of 145 diabetic schoolchildren, 7–20 years old, and 126 matched non‐diabetic controls, certain factors relevant to immunity and diabetes were investigated. The diabetics of all ages were found to have a higher school absenteeism and also, in the prepuberal ages, a higher incidence of acute infectious disease than corresponding non‐diabetics. No major differences in the distribution of common bacterial antibody titers were observed and the formation of agglutinins to tyhoid/paratyphoid vaccine was found to be the same in both groups. The diabetics were carriers of common bacteria somewhat more often than the non‐diabetics. Most results could not be correlated with the degree of diabetic control. It is suggested that the explanation of the differences between the two groups might be a longer voluntary phase of recuperation after acute infectious disease in the diabetics.