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Bone Marrow Studies in Patients Suffering from Infections and Receiving Chloramphenicol
Author(s) -
CHOREMIS C. B.,
MEGAS H. A.,
ASKOUNI A. D.
Publication year - 1963
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1963.tb03754.x
Subject(s) - chloramphenicol , medicine , erythropoiesis , bone marrow , incidence (geometry) , depression (economics) , bone marrow aplasia , hypoplasia , antibiotics , pediatrics , surgery , anemia , microbiology and biotechnology , biology , physics , macroeconomics , optics , economics
SUMMARY The bone marrow of 45 patients suffering from various infections and receiving chloramphenicol, was examined morphologically. Infection alone depressed erythropoiesis in 6 patients. Two patients developed depression of erythropoeiesis while receiving chloramphenicol. One patient developed erythroid hypoplasia ten days after chloramphenicol had been discontinued. Chloramphenicol used in therapeutic doses for a relatively short period of time, is not associated with a high incidence of bone marrow morphological abnormalities.