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Effect of Glucagon on the Plasma Level of Free Fatty Acids
Author(s) -
PERSSON BENGT,
LARSSON YNGVE,
STERKY GÖRAN
Publication year - 1962
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1962.tb08672.x
Subject(s) - medicine , glucagon , endocrinology , diabetes mellitus , obesity , plasma glucose , blood sugar , plasma levels , insulin
Summary The effect of intravenously administrated glucagon on the plasma level of free fatty acids (FFA) and on blood sugar was studied in 24 girls, 11–19 years old, of which 10 had diabetes, 8 had obesity and 6 were controls. Fasting levels of FFA were significantly higher in the diabetes and obesity groups than in the control group. After glucagon there was a decrease of FFA which was more evident in the control and obesity groups than in the diabetes group. The blood sugar response was moderate and identical among the obese and the controls, but more marked and more prolonged among the diabetics. The mechanism behind the effect of glucagon on plasma FFA is discussed.