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A Clinical and Electroencephalographic Study of a Pair of Monozygotic Twins with Phenylketonuria
Author(s) -
HERRLIN KARLMAGNUS
Publication year - 1962
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1962.tb08662.x
Subject(s) - medicine , epilepsy , electroencephalography , monozygotic twin , pediatrics , identical twins , intellectual disability , intelligence quotient , audiology , psychiatry , cognition , genetics , biology
Summary A pair of monozygotic male twins with phenylketonuria, born in 1943, and reared together, were studied clinically and with EEG. Their oligophrenia, epilepsy and EEG findings show appreciable differences. One twin has relatively high intellectual capacity (IQ 55) and 3 per second spike and wave epilepsy, whereas the other is a low grade imbecile (IQ 26) with epilepsy of a focal type. The only known lesional factor is their metabolic disturbance.