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Gamma Globulin against Rubella in Pregnancy: II. Manifest Maternal Rubella in Early Pregnancy Treated with Convalescent Gamma Globulin: a Follow‐Up Study
Author(s) -
LUNDSTRÖM ROLF,
THORÉN CLAES,
BLOMQUIST BERNT
Publication year - 1961
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1961.tb08200.x
Subject(s) - medicine , rubella , pregnancy , gamma globulin , offspring , congenital rubella , obstetrics , antibody , immunology , vaccination , measles , genetics , biology
Summary Rubella convalescent gamma globulin was given to 28 women with rubella in early pregnancy. Of those treated in the first trimester, pregnancy terminated in foetal death in 32% and 11 of 21 offspring survived. At the age of 34 years, four of the 21 survivors showed abnormalities belonging to the rubella syndrome. Administration of antibodies to women with manifest rubella in early pregnancy did not succeed in preventing foetal damage.