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The Extracellular Fluid Volume in Infants and Children
Author(s) -
FRIISHANSEN BENT
Publication year - 1954
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1954.tb04052.x
Subject(s) - extracellular fluid , medicine , body surface area , extracellular , volume (thermodynamics) , body weight , body water , pediatrics , physiology , surgery , biochemistry , chemistry , physics , quantum mechanics
Summary The extracellular volume in fifty infants and children has been studied by a micro modification of the thiosulfate method. This technique was first tried out and it was found that determinations carried out on capillary blood gave the most consistent results. Some limitations of the method are discussed. The extracellular volume was found to diminish rapidly during the first six months of life, from 44 to 30 per cent of body weight, later a gradual decrease during childhood ensued, from 30 per cent to 20 per cent around puberty. When expressed as liters per square meter surface area of the body a less pronounced fall was observed, and only during the first month of life.