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Primary Vitamin D Refractory Rickets I. Report of Two Cases Treated with High Doses of Vitamin D
Author(s) -
WINBERG J.,
BERGSTRAND C. G.,
ENGFELDT B.,
ZETTERSTRÖM R.
Publication year - 1954
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1954.tb04037.x
Subject(s) - rickets , medicine , vitamin d and neurology , vitamin , refractory (planetary science) , calcium , ergocalciferol , disease , vitamin d deficiency , pediatrics , endocrinology , cholecalciferol , physics , astrobiology
Summary 1. Two cases of rickets resistant to vitamin D are described. 2. The effect of massive doses of vitamin D on calcium and phosphate balance is studied. 3. This disease is a well defined clinical entity and the name “Primary Vitamin D Kefractory Rickets” is suggested. The nature of the disease is unknown, but it seems likely that the pathogenetic mechanism is different from that in genuine rickets.