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Selective Filtration of Syphilitic Reagins through the Placenta
Author(s) -
VOGT ELSE
Publication year - 1954
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1954.tb04023.x
Subject(s) - medicine , syphilis , congenital syphilis , titer , placenta , serology , obstetrics , rapid plasma reagin , pregnancy , immunology , fetus , antibody , treponema , human immunodeficiency virus (hiv) , biology , genetics
1 State Institute of Public Health, Serodiagnostic Department (Chief: OTTO HAKTMANN, M.D.), Oslo, Norway Summary Summary Selective filtration of syphilitic reagins through the placenta is studied. Three serologic tests for syphilis performed on the serum from 107 newborn infants are compared with the same tests on the serum from their mothers prior to delivery. Meinicke's clarification reaction (MKR) was negative in the serum from all 107 infants, even where the serum reagin titre of the mother was high at the time of delivery, and the other tests were positive in the serum of the infant. It is concluded that MKR is not suitable for the detection of syphilitic reagins in the serum from newborn infants, because the reaction is always negative.