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Endocardial Fibroejastosis in Infancy
Author(s) -
KISSMEYERNIELSEN F.,
KØLLEJØRGENSEN P.
Publication year - 1954
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1954.tb04003.x
Subject(s) - medicine , endocardial fibroelastosis , endocardium , etiology , autopsy , endocarditis , heart disease , disease , cardiology , pediatrics
Summary Endocardial fibroelastosis was formerly interpreted as a fetal endocarditis, but has later been described under many different names. The etiology is obscure, but the disease is now believed to be a developmental defect. There is an increase in the fibroelastic tissue of the endocardium, usually located in the left side of the heart. Considerable enlargement of the heart is most frequently present, and other concurrent cardiac malformations are not uncommon. The disease is one of infancy. As the diagnosis can be established with certainty only by autopsy, the mortality figures are unknown. In most cases reported in the literature the duration of the disease has been short. The most important clinical signs are cardiac enlargement, dyspnea, cyanosis, atypical murmurs, and dyspepsia. Three cases with typical histological changes are reported.