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Observations on the Cerebrospinal Fluid in Infantile Diarrhea
Author(s) -
HALLMAN NllLO,
TÄHKÄ HILKKA
Publication year - 1952
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1952.tb17051.x
Subject(s) - medicine , diarrhea , cerebrospinal fluid , pediatrics , gastroenterology
Summary 1. A study of the cells in the spinal fluid, as well as Nonne and Pandy reactions, was made in 211 cases of infantile diarrhea of various degree of severity. — 2. The number of cells in C. S. F. was invariably (2–4 examinations) below 5 per cmm in 100 cases, and it was found to be increased at least once as follows: 6–10/cmm in 30 cases, 11–20/cmm in 35, 21–50/cmm in 29, 51–100/cmm in 7, and over 100/cmm in 11 cases. The changes were generally more extensive in the severe cases, but the difference between them and the mildest cases which did not exhibit any symptoms pertaining to the central nervous system, was not particularly significant. — The majority of the cells were diagnosed as lymphocytes. — 3. If the protein reactions are also taken into consideration, the spinal fluid was found within normal limits in only 13 patients. — 4. The age at onset, the weight of the infant as compared with the expected weight, the alkali reserve on admission and other simultaneous infections do not seem to have any noteworthy effect on changes in the spinal fluid. — 5. Changes were found to be more frequent in diarrhea produced by the Shigellas (35 cases) than in other cases due to an unknown causative agent. — 6. Bacterial staining and culture of the C. S. F. were negative in all cases.