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Signs of Sexual Precocity in a Male Infant due to Estrogenic Ointment
Author(s) -
HESSELVIK LENNART
Publication year - 1952
Publication title -
acta pædiatrica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 115
eISSN - 1651-2227
pISSN - 0803-5253
DOI - 10.1111/j.1651-2227.1952.tb17018.x
Subject(s) - medicine , stilbestrol , scrotum , penis , gynecomastia , physiology , dermatology , estrogen , diethylstilbestrol , surgery
Summary A boy, aged 10 months, showed a progressive gynaecomastia, increasing pigmentation of areolae mammae, penis and scrotum, and growth of sexual hair. The symptoms were caused by percutaneous absorption of stilbestrol. The identical picture was demonstrated experimentally in another case. — The mechanism of development of the syndrome is briefly discussed.